Bioengineering and Toxicology Seminar Academic Year 2020-21

Spring 2021

Feb 5, 2021 - 12:00 PM

Synthetic Genetic Feedback Control Circuits to Reprogram Cell Fate

The Effect of a Probiotic on Mutations Induced by a Methylating Agent

Feb 12, 2021 - 12:00 PM

Identifying Correlates of Tuberculosis Protection Mediated by BCG in Collaborative Cross Mice

Understanding and Re-engineering Enzymes Using Molecular Dynamics

Feb 19, 2021 - 12:00 PM

EGFR Inhibitors as Host-directed Therapies for Tuberculosis

Investigating Extracerebral Influences on Brain Dynamics Using Extended fMRI

Feb 26, 2021 - 12:00 PM

Identifying Intracellular Networks Related to Antigen Presentation in Glioblastoma

Making Sense of Mass – an Ongoing Story on T Cell Buoyant Mass Heterogeneity

Mar 12, 2021 - 12:00 PM

Enzyme Evolution for Unnatural Porphyrin Synthesis

Cephalopod Lenses: A Route to Bioinspired Optical Materials

Mar 26, 2021 - 12:00 PM

Developing High-throughput, Quantitative Platforms to Identify the Targets of Small Molecules

Tool Development for Studying Peptide-MHCII Binding in a Globally-Representative Manner

Apr 2, 2021 - 12:00 PM

Engineering a Mammalian Toggle Switch that Functions over Long Time Scales

Enhancing Local Delivery of Cancer Immunotherapy with Alum Adjuvant

Apr 9, 2021 - 12:00 PM

Whole-cell Bacterial Sensors for Environmental DNA Detection

Design of Self-assembling Enzymatically Modified Peptides to Reproduce Cephalopod Dynamic Coloration

Apr 16, 2021 - 12:00 PM

Single-cell Analysis Reveals the Subthreshold TLR Response to Mycobacterium tuberculosis Infection

Structural Mapping of the Zebrafish Habenula

Apr 23, 2021 - 12:00 PM

Identifying Regulators of Synaptogenesis with Optical Pooled Screens

Towards Multimodal Interrogation of Olfactory-driven Behaviors In The Zebrafish Brain

Apr 30, 2021 - 12:00 PM

Investigation of MAPK Inhibition Using Analog-sensitive Kinase

Developing a Novel Cell Collection Method for Lineage Sequencing

May 14, 2021 - 12:00 PM

Mucin Glycans Shape Complex Microbial Communities

Engineering a Tumor-localized Antioxidant Enzyme for Cancer Therapy

May 21, 2021 - 12:00 PM

Engineering CRISPR-associated Transposons to Re-wire and Control Natural and Synthetic Gene Networks

Development of SARS-CoV-2 Humoral Immunity Across Disease Severity

May 28, 2021 - 12:00 PM

Compact RNA Editors Using Small Cas13 Proteins

Jun 11, 2021 - 12:00 PM

Creating a New Malaria Vaccine by Displaying Antigens on the Parasite Surface

Inflammatory Mediators Characterize Donor-specific Response to Dexamethasone in Human PTOA Model

Jun 11, 2021 - 1:00 PM

Interrogating Macrophage States in Tuberculosis

Fall 2020

Sep 4, 2020 - 12:00 PM

Wearable Cell-Free Synthetic Biology

Screening for Lethality: Discovering Therapeutic Strategies Against Antibiotic Tolerant Bacteria

Sep 11, 2020 - 12:00 PM

Identifying Pathways that Control Cell Fate After DNA Damage

Genome Mining for the Discovery of Modular Molecular Systems

Sep 18, 2020 - 12:00 PM

Engineering Plant-microbe Communication

Driving Strong Type I Interferon Signaling for Cancer Immunotherapy

Sep 25, 2020 - 12:00 PM

Identifying ALS Disease Progression Subtypes

A Nucleic Acid Origami Approach to Probing RNA Tertiary Structure

Oct 9, 2020 - 12:00 PM

Selection for Modified Peptide Inhibitors of the SARS-CoV-2 Papain-like Protease

Molecular Computation with FRET-based Neural Networks

Oct 16, 2020 - 12:00 PM

Identifying Neural Network Architectures for Genomics Prediction Tasks Using Simulated Data

Engineering Viruses to Decode and Reprogram Immunity

Oct 23, 2020 - 12:00 PM

Design and Characterization of DNA Origami for Immunostimulation

Isolating Signal Peptide-mediated Selection Bias in Yeast Display

Oct 30, 2020 - 12:00 PM

Mechanistic Characterization of the Epidermal Growth Factor Receptor Signaling Network

PrimeDesign Software for Rapid and Simplified Design of Prime Editing Guide RNAs

Nov 6, 2020 - 12:00 PM

Discovery and Engineering of Acutumine-type Alkaloids In Menispermaceae Plants

Screening for Antibacterial Combination Therapies

Nov 13, 2020 - 12:00 PM

Wastewater Surveillance to Monitor the COVID-19 Pandemic

Protein Delivery with a Bacterial Contractile Injection System

Nov 20, 2020 - 12:00 PM

Engineering Probiotics for the Modulation of Bile Acid Metabolism

Small Animal fMRI Biofeedback

Dec 4, 2020 - 12:00 PM

CRISPR Beyond Adaptive Immunity: RNA-guided Transposition

New (Old?) Tools for Synthetic Biology in Malaria Parasites

Dec 11, 2020 - 12:00 PM

A Low-cost COVID-19 Vaccine Candidate

Computationally-assisted Discovery and Design of New Antibiotics

Dec 18, 2020 - 12:00 PM

Exploring Virus-like Proteins in Mammalian Genomes

Compromised SARS-CoV-2-specific Placental Antibody Transfer