Seminars

Heavy industrial activity releases toxic amounts of arsenic into the environment, affecting the health of local communities and global agricultural infrastructure. The ability to monitor arsenic levels with high spatial and temporal granularity requires quantitative, field-deployable sensors, but current methods are either prohibitively expensive, centralized, or qualitative. Here, we engineer electroactive bacteria to link arsenic biosensing architecture to quantitative electrochemical signals on low-cost, screen-printed electrodes.

The MYC family plays critical roles in cancer, yet L-MYC remains comparatively understudied despite its involvement in aggressive neuroendocrine malignancies. Its intrinsically disordered nature presents challenges for conventional drug discovery. This talk explores the biological rationale for targeting L-MYC and strategies to identify and validate small-molecule binders using small-molecule microarrays and biophysical assays.