Seminars

Biomaterials have become increasingly multifunctional and complex, bringing both breakthroughs and challenges in medicine. One of the greatest issues is the difficulty in assessing multidimensional dynamics of tissue–implant interactions due to a lack of noninvasive and multiplexed monitoring techniques. To address this, we developed a surface-enhancing Raman-active implant material composed of gold nanocolumns on a titanium surface (AuNC-Ti) for enabling nondestructive monitoring of complex implant-material interactions in real-time.