Open Staff Positions
POSTDOCTORAL ASSOCIATE, MAMMALIAN SYNTHETIC BIOLOGY, Biological Engineering, Synthetic Biology Center-Weiss Lab –Weiss Lab, to join a research lab focused on engineering integrated biological circuits and elucidating design principles for complex cellular systems through protein phosphorylation networks and cell signaling. Will work closely with researchers, principal investigators, and lab management on a government-sponsored DARPA program developing mammalian synthetic biology approaches for therapeutic cell engineering. This role combines rigorous mechanistic science with circuit-level problem solving and offers potential for high-impact publications. Projects involve building mammalian genetic circuits in red blood cell progenitors that sense extracellular biomarkers (pH, lactate) through engineered GPCRs and implement multi-layer phosphorylation-based decision logic (AND/OR gates) to drive precise metabolic and physiological responses. Will design genetic circuits and bio-assays; engineer orthogonal kinase-substrate pairs and split-enzyme systems; collect and analyze data using techniques such as flow cytometry, RT-qPCR, next-generation sequencing, ELISA, and immunofluorescence; characterize protein localization, phosphorylation state, and stability in RBCs. Position includes collaboration with cross-functional multi-university teams on functional validation in physiologically relevant conditions. Job Number: 25600
Description, requirements, and details here.
POSTDOCTORAL ASSOCIATE, Bathe Lab, to work on PRISM (Probe-based Imaging for Sequential Multiplexing), a multimodal synaptomics platform developed in the lab that simultaneously measures synaptic protein composition, local mRNA translation, and synaptic activity at single-synapse resolution. This is an exciting opportunity to help answer fundamental questions about how neuropsychiatric diseases such as schizophrenia and autism manifest at the synapse in human neurons, and whether those changes can be pharmacologically reversed. The postdoc will play a central role in extending PRISM into human iPSC-derived neurons for scalable, automated drug screening. Core responsibilities span neuronal cell culture, multiplexed imaging assay development, automation of liquid-handling and imaging workflows, and computational analysis of high-content synaptic datasets. The position sits at the intersection of technology development, translational neuroscience, and drug discovery. Job Number: 25864
Description, requirements, and details here.
TECHNICAL ASSOCIATE II, Biological Engineering (Griffith lab) and The SHED at MIT, to join the Hardware Innovation Team in a joint position supporting advanced fabrication, prototyping, and precision manufacturing efforts. Working closely with engineering collaborators, faculty, researchers, and technical staff, this individual will play a central role in the physical manufacturing, microscopic inspection, and high-tolerance optimization of next-generation hardware platforms. Job Number: 25845
Description, requirements, and details here.
POSTDOCTORAL ASSOCIATE, MICROFLUIDICS AND BIOFABRICATION, Biological Engineering – Weiss Lab, to join an interdisciplinary research environment focused on microfluidics, biofabrication, and advanced in vitro systems. Will work closely with faculty, researchers, and technical staff on projects at the interface of engineering, biology, and biomaterials, with an emphasis on developing and implementing experimental platforms that support human-relevant research. The role will involve designing and testing perfusion-enabled systems, developing and optimizing biomaterials and biofabricated constructs, and contributing to interdisciplinary projects involving microfluidics, 3D bioprinting, organoid-based models, and related technologies. Job Number: 25784
Description, requirements, and details here.
POSTDOCTORAL ASSOCIATE, MAMMALIAN SYNTHETIC BIOLOGY, Biological Engineering – Weiss Lab, to join an interdisciplinary academic research lab focused on creating integrated biological systems capable of autonomously performing useful tasks and elucidating design principles for engineering complex cellular and tissue phenotypes; design, build, and test mammalian synthetic gene circuits, including sensing modules (e.g., RNA/miRNA/metabolite-responsive elements), logic/control elements, and output programs that drive measurable cellular behaviors; engineer and maintain mammalian cell lines; perform genome engineering and targeted integration workflows; validate engineered lines using standard molecular and cellular assays; and plan and execute experiments to characterize circuit performance using flow cytometry, microscopy, RT-qPCR, sequencing-based readouts, ELISA, and related methods. Job Number: 25641
Description, requirements, and details on MIT HR Job Openings.
LEADERSHIP GIVING OFFICER, Biological Engineering (BE), will create and execute a comprehensive, strategic development plan designed to raise awareness, strengthen relationships, and garner financial support for BE’s initiatives and academic programs; manage, build, and execute successful fundraising strategies for a mature portfolio (including Core Team), creating individualized solicitation plans leading to major and principal gifts in support of MIT’s fundraising priorities, capital projects, and other departmental priorities; work collaboratively to increase the visibility of BE and establish a thriving community of supporters, including both philanthropic and industry partnerships; take part in face-to-face donor/industry partner/prospect visits, arrange faculty meetings, site tours, and events, draft high-level proposals, create materials, and disseminate content and collateral related to BE; and help maximize the Department Head’s/faculty travel to engage with prospective donors and industry partners. Job Number: 24952
Description, requirements, and details on MIT HR Job Openings.
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