Bioengineering and Toxicology Seminar Academic Year 2016-17

Fall 2016

Sep 16, 2016 - 12:00 PM 32-155

Small Molecule Targeting of FOXA1 in Hormone-dependent Cancers

Gastroretentive Devices for Large Dose Drug Delivery

Sep 23, 2016 - 12:00 PM 32-155

Design of Silica Structures Using Post-Translationally Modified Peptides from Diatoms

Design of Cartilage Penetrating Nanoparticles

Sep 30, 2016 - 12:00 PM 32-155

A CRISPR Screen to Identify Combination Therapies for Improved Treatment of Ovarian Cancer

Characterization of Multi-drug Resistant Enterococcus faecalis Isolated from Research Macaques

Oct 7, 2016 - 12:00 PM 32-155

Engineering Rational Modification of Ribosomally Synthesized Peptides as a Source of Novel Drugs

Phosphotyrosine Signaling in Alzheimer’s Disease

Oct 14, 2016 - 12:00 PM 32-155

Cell-Free Genetic Sensors to Monitor Gut Microbes

The Human Gut Microbiome in Health and Disease

Oct 21, 2016 - 12:00 PM 32-155

Engineering Physiologically Relevant In Vitro Liver Models

Engineering Nanobody CAR T-cells for Increased Targeting Specificity and Treatment of Solid Tumors

Oct 28, 2016 - 12:00 PM 32-155

Tumor/Macrophage Crosstalk in Ovarian Cancer Kinase Inhibitor Resistance

Sso7d Fusion Proteins as Novel EGFR Antagonists

Nov 4, 2016 - 12:00 PM 32-155

A Novel Platform for the Engineering of Bispecific Antibodies Using Structure-based Design

Tough Hydrogel-based Capsules for Deployment of Engineered Organisms

Nov 18, 2016 - 12:00 PM 32-155

Developing Bioremediation Strategies Using Yeast

Spatial Multi-Omics in Entire Animals of C. elegans

Dec 2, 2016 - 12:00 PM 32-155

Synthetic Hydrogels for Studying Morphogenesis in Engineered Multicellular Systems

A Path to Genome-wide Chromatin Conformation Imaging

Dec 9, 2016 - 12:00 PM 32-155

Enhancing the CRISPR-Cas Genome Engineering Toolbox

Environment-mediated Drug resistance Mechanisms in the Liver Tumor Microenvironment

Dec 16, 2016 - 12:00 PM 32-155

Genome-scale Activation of LncRNA Loci Identifies Novel Vemurafenib Resistance Mediators

Understanding and Mitigating the Effects of Limiting Transcriptional Resources in Biological Systems

Spring 2017

Feb 17, 2017 - 12:00 PM 32-141

Epitranscriptomics: A System of tRNA Modifications Control Mycobacterial Drug Resistance

The Megakaryocyte: A New Innate Immune Cell and Its Potential Role in Sepsis

Feb 24, 2017 - 12:00 PM 32-141

Nanoscale Mapping of RNA via Expansion Microscopy

Temporal Programming of Cancer Immunotherapy Agents to Optimize Efficacy and Toxicity

Mar 3, 2017 - 12:00 PM 32-141

Dynamic Metabolic Engineering in Bacteria Using Quorum Sensing Circuits

Noninvasive Prediction of Aggressive Prostate Cancer Through Protease Nanosensors

Mar 17, 2017 - 12:00 PM 32-141

Oil-isolated Hydrogel Microparticles for Bioassays

Dormant Bacteria Resuscitate and Colonize the Human Gut Microbiota After Perturbation

Mar 24, 2017 - 12:00 PM 32-141

Discovery and Characterization of an Epigenomic Signature of Late-stage Cellular Differentiation

Liposomal MRI Contrast Agents: A Novel Architecture for Neurotransmitter Sensors

Apr 7, 2017 - 12:00 PM 32-141

Identification of Dysregulated Signaling Events in Medulloblastoma

Characterizing Viscoelastic Mechanical Properties of Biological Soft Tissues With Impact Indentation

Apr 14, 2017 - 12:00 PM 32-141

High-throughput Sequencing of T Cell Receptor Variable Region

Behavioral and Transcriptional Response of a Coral Pathogen to Coral Mucus

Apr 21, 2017 - 12:00 PM 32-141

Utilizing Protein Carriers to Engineer More Potent Cancer Vaccines

Microbial Hitchhiking Promotes Dispersal and Colonization of New Niches by Staphylococci

Apr 28, 2017 - 12:00 PM 32-141

Population-level Tumor Growth Inhibition Modeling

Building Single-cell Biomolecule Sensors

May 5, 2017 - 12:00 PM 32-141

Discovery of a MAX Binder That Modulates c-MYC Activity in Cancer

Engineering Synthetic RNA Circuits for Small Molecule Responsive Expression

May 12, 2017 - 12:00 PM 32-141

Quantitative Time Lapse Analysis of Intracolony Heterogeneity in Mesenchymal Stromal Cell Cultures

Cellular Self-reporting