Speaker:
Title:
Engineering M13 Bacteriophage Platforms for Tumor Imaging and Therapy Applications
Abstract:
We are expanding on the functionality of M13 bacteriophage as an engineerable nanotheragnostic for medical imaging and therapy applications, particularly in the case of difficult to reach tumors such as glioma. In two parts, I will first describe the assembly of M13 of smaller sizes, termed ‘inho’ phages, and second, blood brain barrier crossing with chlorotoxin peptide display on the capsid of M13.