
Alice (née Macdonald) Walsh
Bachelor of Science in Biological Engineering, MIT, 2008
Professional Experience
Head, Analytics Innovation, Oncology Translational Bioinformatics
- Bristol-Myers Squibb
- Managed group of three PhD scientists tasked with integrating internal and external datasets and designing research questions to inform immuno-oncology programs across tumor indications
- Major projects included generating immune repertoire sequencing data, establishing single-cell analytic platforms, and evaluating novel neoantigen prediction methodologies
Senior Scientist
- Janssen Research & Development
- Led internal and external projects with both commercial research organizations and academic PIs
- Analyzed biomarker data from phase II and phase III rheumatology clinical studies
- Launched internal web-based tools for accessing biomarker datasets
- Built gene transcriptional networks and developed methods for target identification from network models of rheumatoid arthritis
- Generated drug-target networks and methods for evaluating drug combinations in vitro
- Authored multiple manuscripts (ref 1-6 below) and presented at national and international meetings
Intern
- Merck
Educational Experience
Academic:
- Teaching Assistant: Thermodynamics of Biomolecular Systems - 20.110
- Taught Intro to MATLAB short course targeted to Biological Engineering applications
Participation in Programs:
- MIT Undergraduate Research Opportunities Program
- MIT International Science and Technology Initiatives
Undergraduate Research Experiences:
- Voldman Lab: Helped develop a simple cell patterning technique to better control studies of cellular contact in vitro.
- Lauffenburger Lab: developed a model of cell migration that simulated recent experimental results that had been published by collaborators.
- Le Laboratoire, an art-science initiative in Paris, France
- Internship at École supérieure de physique et de chimie industrielles de la Ville de Paris, France
Publications/Posters:
- Google scholar page: https://scholar.google.com/citations?user=G9Icw9EAAAAJ&hl=en
Activities, interests and hobbies:
Local core team member of the Women’s Leadership Initiative, an Janssen employee resource group. More recently, I have become involved in the R-Ladies (rladies.org) movement. I started the Philadelphia chapter for R-Ladies (rladiesphilly.org), where we promote engagement and leadership among gender minorities in the R statistical programming community.
Additional Degrees:
Ph.D. in Bioengineering, University of Pennsylvania