Speaker:
Title:
Identifying Targeted Therapeutic Candidates in Brain Tumors
Abstract:
Medulloblastoma (MB) is one of the most common malignant pediatric brain tumors and demands identification of targeted therapies for improved patient outcome. Immunotherapy has emerged as an effective therapeutic option in recent decades but has demonstrated little success in solid brain tumors. Unfortunately, there is no consensus on the mechanism of immune evasion which MB tumors employ. We propose a novel spatial mapping of tumor-immune interactions in MB for the identification of potential therapeutic avenues.