BATS

Date/Time:

Feb 19, 2021 - 12:00 PM

Location:

Hosts:

Bevin Engelward

Speaker:

Title:

EGFR Inhibitors as Host-directed Therapies for Tuberculosis

Abstract:

Tuberculosis is the leading cause of infectious disease death. During infection, macrophages phagocytose bacteria and either successfully control infection or become a niche for replication. Host-directed therapies (HDTs) improve macrophages’ control of infection. However, HDTs act via unclear mechanisms, and many HDT-induced antimicrobial responses are dispensable for control. Here, I describe ongoing work characterizing EGFR inhibitors as HDTs and defining their mechanisms of action.

Speaker:

Title:

Investigating Extracerebral Influences on Brain Dynamics Using Extended fMRI

Abstract:

Modern day neuroscience is heavily focused on understanding the ways in which brain regions interact with each other to produce higher-order functions. However, the brain does not exist alone and is influenced by peripheral inputs throughout the body. We propose a combination of molecular sensors and functional MRI techniques called “extended fMRI” to understand extracerebral influences on brain dynamics.