Technical Electives at MIT: 

  • Mechanisms of Drug Actions - 20.201
  • Molecular and Engineering Aspects of Biotechnology - 20.361

Maryelise Cieslewicz

Bachelor of Science in Biological Engineering, MIT, 2010

Professional Experience

Project Manager
  • Pharmacyclics - An AbbVie Company
  • Facilitate Research and Development Leadership Team meetings chaired by President
  • Support preclinical research teams through research timeline management, governance meeting facilitation, and data transfer
Consultant
  • Boston Consulting Group
  • Broad biopharma corporate strategy consulting experience

Educational Experience

Academic: 

  • Biological Engineering Undergraduate Board: President, Secretary
  • Teaching Assistant: Fields, Forces and Flows in Biological Systems - 20.330

Participation in Programs: 

  • MIT Undergraduate Research Opportunities Program
  • Amgen Scholars Program

Undergraduate Research Experiences: 

  • Wittrup Lab - Characterized a bispecific antibody for targeted delivery of radionuclides to cancer
  • Dewey Lab - Quantified the thickness and mechanical properties of glycocalyx on endothelial cells

Publications/Posters: 

PUBLICATIONS

  • KD Orcutt, M Ackerman, M Cieslewicz, E Quiroz, AL Slusarczyk, J Frangioni and KD Wittrup. A Simple Modular IgG-like Bispecific Antibody Topology. Protein Eng. Des. Sel., April 2010; 23: 221 - 228.
  • KD Orcutt, AL Slusarczyk, M Cieslewicz, B Ruiz-Yi, KR Bhushan, JV Frangioni, and KD Wittrup. Engineering an antibody with picomolar affinity to DOTA chelates of multiple radionuclides for pretargeted radioimmunotherapy and imaging.┬áNucl Med Biol., February 2011; 38(2):223-233

POSTERS

  • M Cieslewicz, KD Orcutt, KD Wittrup. Effective Strategy for Targeting Shed Antigen. SWE National Conference, 2009. (Collegiate Poster Competition Finalist)
  • M Cieslewicz, KD Orcutt, KD Wittrup. Effective Strategy for Targeting Shed Antigen. Boston Undergraduate Research Symposium, 2009. (poster presentation)

PRESENTATIONS (Presenter denoted by an asterisk)

  • Y Yao, H Huang*, M Cieslewicz, and CF Dewey. Three-dimensional mapping of the glycocalyx layer on endothelial cells. Biomedical Engineering Society, 2007 Annual Fall Meeting. (oral presentation)
  • Y Yao, M Cieslewicz, H Huang, ER Damiano, and CF Dewey*. Dynamics of the endothelial glycocalyx layer subjected to unsteady flow. Biomedical Engineering Society, 2007 Annual Fall Meeting. (oral presentation)