Alice (née Macdonald) Walsh

Bachelor of Science in Biological Engineering, MIT, 2008

Professional Experience

Head, Analytics Innovation, Oncology Translational Bioinformatics
  • Bristol-Myers Squibb
  • Managed group of three PhD scientists tasked with integrating internal and external datasets and designing research questions to inform immuno-oncology programs across tumor indications
  • Major projects included generating immune repertoire sequencing data, establishing single-cell analytic platforms, and evaluating novel neoantigen prediction methodologies
Senior Scientist
  • Janssen Research & Development
  • Led internal and external projects with both commercial research organizations and academic PIs
  • Analyzed biomarker data from phase II and phase III rheumatology clinical studies
  • Launched internal web-based tools for accessing biomarker datasets
  • Built gene transcriptional networks and developed methods for target identification from network models of rheumatoid arthritis
  • Generated drug-target networks and methods for evaluating drug combinations in vitro
  • Authored multiple manuscripts (ref 1-6 below) and presented at national and international meetings
  • Merck

Educational Experience


  • Teaching Assistant: Thermodynamics of Biomolecular Systems - 20.110
  • Taught Intro to MATLAB short course targeted to Biological Engineering applications

Participation in Programs: 

  • MIT Undergraduate Research Opportunities Program
  • MIT International Science and Technology Initiatives

Undergraduate Research Experiences: 

  • Voldman Lab: Helped develop a simple cell patterning technique to better control studies of cellular contact in vitro.
  • Lauffenburger Lab: developed a model of cell migration that simulated recent experimental results that had been published by collaborators.
  • Le Laboratoire, an art-science initiative in Paris, France
  • Internship at École supérieure de physique et de chimie industrielles de la Ville de Paris, France


Activities, interests and hobbies: 

Local core team member of the Women’s Leadership Initiative, an Janssen employee resource group. More recently, I have become involved in the R-Ladies ( movement. I started the Philadelphia chapter for R-Ladies (, where we promote engagement and leadership among gender minorities in the R statistical programming community.

Additional Degrees: 

Ph.D. in Bioengineering, University of Pennsylvania