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October 17, 2025 Seminar
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Riyam Al Msari
Wittrup Lab Irvine LabDespite advances in immunotherapies that boost T-cell function, many tumors remain resistant due to suppression by tumor-associated myeloid cells that dominate the microenvironment and inhibit T-cell activity. Interferon-γ can reprogram them into pro-inflammatory, T-cell-supportive states, but its use is limited by systemic toxicity and pleiotropic activation of other cells. We developed a protein-engineering strategy that confines Interferon-γ activity on myeloid cells only, restoring T cell function while minimizing off-target activation.
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Valeria Márquez-Pellegrin
Belcher Lab DeKosky LabBreast cancer is a highly prevalent and heterogeneous disease, with some subtypes showing low immunogenicity and others lacking actionable targets. Through this project, we envision to 1) map the breast cancer TCR landscape using a high-throughput flow-focusing approach, and to 2) develop a therapeutic capable of eliciting a robust immune response using E. coli Nissle 1917-derived minicells.
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October 23, 2025 Seminar
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Gabriel Rocklin
Large-scale Discovery of Protein Folding Stability and Conformational Dynamics
October 24, 2025 Seminar
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Tran Luu
Stark Lab -
Brian Cho
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October 31, 2025 Seminar
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Sarah Sobol
Wittrup Lab DeKosky Lab -
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November 6, 2025 Seminar
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Lukasz Bugaj
Using Light, Temperature, and Protein Condensation To Understand and Control Cells
November 7, 2025 Seminar
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Lauren (Ren) Ramlan
Voigt Lab Kong Lab -
Sophie VanderWeele
Hansen Lab Page Lab
November 14, 2025 Seminar
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Anna Lapteva
Langer Lab Anderson Lab -
Allison Glynn
Raines Lab