Speaker:
Title:
Toward Building Liver: Engineering Solutions for Scalable Tissue Constructs
Abstract:
Liver failure is only curable by donor transplantation, which is limited by a severe donor organ shortage. Alternatively, cell-based therapies have curative potential, though they face several challenges at scale including achieving phenotypic stability and vascularization. In this work, we build upon a series of ‘tools’ from our lab that utilize fibroblast co-culture to enable the study of hepatic tissue ex vivo, with an end goal of building artificial liver implants.