Asmamaw (Oz) Wassie (BOYDEN LAB)

Nanoscale Mapping of RNA via Expansion Microscopy

The ability to image RNA identity and location with nanoscale precision throughout tissues would enable the molecular characterization of cell types, sub-cellular compartments, and signaling pathways, in normal as well as pathological states. We have developed an approach called Expansion FISH (ExFISH), which uses Expansion Microscopy to enable the super-resolution imaging of RNA structure and location with diffraction-limited microscopes in thick specimens.

Adrienne Rothschilds (WITTRUP LAB)

Temporal Programming of Cancer Immunotherapy Agents to Optimize Efficacy and Toxicity

The ability to image RNA identity and location with nanoscale precision throughout tissues would enable the molecular characterization of cell types, sub-cellular compartments, and signaling pathways, in normal as well as pathological states. We have developed an approach called Expansion FISH (ExFISH), which uses Expansion Microscopy to enable the super-resolution imaging of RNA structure and location with diffraction-limited microscopes in thick specimens.